Patents and certifications, etc


Patent registration related to wild ginseng culture root

  • Wild ginseng culture root oil with increased fatty acid content and manufacturing method 1
  • Wild ginseng culture root oil with increased fatty acid content and manufacturing method 2
  • Nano-emulsion containing fermented products of wild ginseng culture root extract with enhanced antioxidant effect. And a cosmetic composition for skincare, including this nano emulsion.
  • Method for producing a nano-emulsion containing fermented wild ginseng root. And a cosmetic composition for skin whitening including this nano-emulsion.
  • Manufacturing method of fermented wild ginseng cultured root with enhanced specific ginsenoside content
  • Method for manufacturing fermented wild ginseng cultured root powder using pediococcus pentosaceus HLJG0702 strain
  • Manufacturing method of fermented wild ginseng cultured root with enhanced content of specific phenol compounds
  • Method for producing a wild ginseng cultured root extract with increased ginsenoside content through organic acid treatment. And wild ginseng cultured root extract produced by the same method.
  • Crushing method of ginseng powder to improve ginsenoside extraction efficiency
  • Nano-emulsion cosmetic composition for skin moisturizing including a fermented wild ginseng root extract with enhanced antioxidant effect

Patent application related to wild ginseng culture root

  • A method for producing a fermented wild ginseng root extract with an increased content of low molecular weight ginsenosides. And the fermented product of cultured wild ginseng root extract with increased low molecular weight ginsenoside content produced in the same way as above.

ICID

  • Saccharomyces/Panax Ginseng Adventitious Root Oil Ferment Filtrate Extract
  • Pediococcus/Panax Ginseng Adventitious Root Extract Ferment Extract 

KCID

  • Pediococcus / Wild ginseng cultured root extract fermented extract
  • Yeast / Wild ginseng cultured root oil fermented filtered extract
Thesis

Enhancement of ginsenoside content and component conversion of wild ginseng cultured root (Jae-geun Lee, who is research institute director of Hwajin Bio Cosmetics, was awarded in the agricultural and fishery category among 250 recipients of the 2021 Korea Science and Technology Excellence Paper Award)

Jae-geun Lee, who is research institute director of Hwajin Bio Cosmetics, was awarded in the agricultural and fishery category among 250 recipients of the 2021 Korea Science and Technology Excellence Paper Award.

"Enhancement of ginsenoside content and component conversion of wild ginseng cultured root "

Physiological activity test of fermented wild ginseng culture root supercritical fluid extract


Hyun-Min Ko, Kyeoung-Cheol Kim, Ju-Sung Kim(Majors in Plant Resource and Environment College of Agriculture and Life Science, SARI of Jeju national university), Tae-Kil Eom(*Subtropical/tropical organism gene bank of Jeju national University), Ji Hye Yoo(Bioherb research institute of Gangwon national university), Jung Dae Lim(Department of herbal medicine resource, Gangwon national university), Chang Yeon Yu(Department of bio-resource science of Gangwon national university), Jae Geun Lee(Hwajin Biocosmetics)

Changes in physiological activity of fermented wild ginseng cultured roots treated with microorganisms


Chul-Joong Kim, Jae-Geun Lee, Nam-Jun Kim (Hwajin Biocosmetics), Sung Eunsu (Department of medicinal plants of Suwon women's university), Ji-Hye Yoo, Chang-Yeon Yoo (Department of biological resources science of Gangwon national university), Choi Seon-Kang (Department of agriculture and life science of Gangwon national university) ; Jeongdae Lim (Department of herbal medicine resources development of Gangwon national university)

Extraction of low molecular weight ginsenosides from wild ginseng culture root by steam processing.


Yeji Lee, Arreum Jo, Cheoljoong Kim, Jaegeun Lee (Hwajin Biocosmetics), Heekyu Kim (Gangwon provincial forest science research institute), Eunji Ko, Jeongdae Lim (Department of herbal medicine resources development of Gangwon national university), Jaehoo Choi, Changyeon Yoo (Department of agriculture and life industry of Gangwon national university), Seon-Kang Choi (Department of agriculture and life industry of Gangwon national university)

Changes in the content of non-saponin fatty acids by yeast treatment of wild ginseng culture root oil extracted with supercritical fluid. And enhanced Collagenase and Elastase inhibitory activity.


Chul-joong Kim, Jae-kwon Shim, Gyeong-cheol Kwon, Jae-geun Lee (Hwajin Biocosmetics), Jeongdae Lim (Department of herbal medicine resources development of Gangwon national university), Seon-Kang Choi (Department of agriculture and life industry of Gangwon national university), Changyeon Yoo (Department of agriculture) and life industry of Gangwon national university)

Antioxidant effect of fermented wild ginseng cultured root concentrate and protective effect on PC12 cytotoxicity induced by hydrogen peroxide


Choi, Yeo-Ok (Bio-Biotechnology research institute) ; Yuri Kim, Seungyong Shin, Byeongju Kang, Kwansu Kim, Jieun Choi (Ji Biopharm Co., Ltd.), Jaegeun Lee, Cheoljoong Kim, Yeji Lee (Hwajin Biocosmetics), Beomseok Han (Faculty of food and pharmaceutical engineering of Hoseo university)

Antioxidant effects and tyrosinase and

elastase inhibitory activities of mountain

ginseng adventitious roots extracts at

different ethanol concentrations

Hyun Min Ko1, Tae Kil Eom2, Kyeoung Cheol Kim1, Chul Joong Kim3, Jae Geun Lee3, Ju-Sung Kim1*

1Major in Plant Resource and Environment, SARI, Jeju National University, Jeju 63243, Korea

2Subtropical/Tropical Organism Gene Bank, SARI, Jeju National University, Jeju 63243, Korea

3Hwajin Cosmetics, Hongcheon 25142, Korea

Ginsenosides Rg5 and Rk1 Enriched CulturedWild

Ginseng Root Extract Bioconversion of Pediococcus

pentosaceus HLJG0702: Effect on Scopolamine-Induced

Memory Dysfunction inMice

Kyu Sup An 1,y, Yeo Ok Choi 2,y, So Min Lee 1, Hyeon Yeol Ryu 1, Su Jin Kang 1, Yong Yeon 1,

Yu Ri Kim 3, Jae Geun Lee 4, Chul Joong Kim 4, Ye ji Lee 4, Byeong Ju Kang 3, Jee Eun Choi 3

and Kyung Seuk Song 1,*

Changes of biological activities of rhizome and leaves of polygonatum sibiricum redoute according to steaming time and temperature


Youngseon Oh, Jaehoo Choi, Cheoljoong Kim, Jaegeun Lee (Hwajin Biocosmetics), Sung Eunsu (Department of medicinal plants of Suwon women's university), Myeongjo Kim (Department of biological resources science of Gangwon national university) ; Chang-Yeon Yoo (Department of biological resources science of Gangwon national university)

Changes of Biological Activities of Rhizome and Leaves of Polygonatum sibiricum

Redoute according to Steaming Time and Temperature

Yeong Seon Oh1, Jae Hoo Choi2, Chul Joong Kim3, Eun Soo Seong4,

Myong Jo Kim5, Chang Yeon Yu6 and Jae Geun Lee7†

The Isoflavonoid Constituents and Biological Active of Astragalus Radix by Fermentation of β-glucosidase Strains


Cheoljoong Kim, Jaehoo Choi, Jaegeun Lee (Hwajin Biocosmetics), Sung Eunsu (Department of medicinal plants of Suwon women's university), Jeongdae Lim (Department of herbal medicine resources development of Gangwon national university),Choi Seon-Kang (Department of agriculture and life science of Gangwon national university), Chang-Yeon Yoo (Department of biological resources science of Gangwon national university)

The Isoflavonoid Constituents and Biological Active of Astragalus Radix by

Fermentation of β-glucosidase Strains

Chul Joong Kim1, Jae Hoo Choi2, Eun Soo Seong3, Jung Dae Lim4, Seon Kang Choi5,

Chang Yeon Yu6 and Jae Geun Lee7†

Biological Activities and Anti-wrinkle Effects of Pinus koraiensis Siebold et Zucc Leaf Extract


Gyeong-cheol Kwon, Youngseon Oh, Cheoljoong Kim, Jae-geun Lee (Hwajin Biocosmetics), Chang-Yeon Yoo (Department of biological resources science of Gangwon national university)

Biological Activities and Anti-wrinkle Effects of

Pinus koraiensis Siebold et Zucc. Leaf Extract

Kyung Cheol Kwon1#, Yeong Seon Oh2#, Chul Joong Kim3, Chang Yeon Yu4 and Jae Geun Lee5†

Neuroprotective Effect and Antioxidant Potency of Fermented

Cultured Wild Ginseng Root Extracts of Panax ginseng C.A.

Meyer in Mice

Chul-Joong Kim 1,† , Hyeon-Yeol Ryu 2,† , Somin Lee 2 , Han-Joo Lee 3 , Yoon-Soek Chun 3 ,

Jong-Kyu Kim 3 , Chang-Yeon Yu 4, Bimal Kumar Ghimire 5 and Jae-Geun Lee 1,*